Standard versus double dosing of beta-lactam antibiotics in critically ill patients with sepsis: The BULLSEYE study protocol for a multicenter randomized controlled trial

Table 2 Maximum dosages intervention arm

	Loading dose^a	Daily dose
Cefotaxime	2000 mg	8000 mg
Ceftazidime	2000 mg	6000 mg
Ceftriaxone	2000 mg	4000 mg
Cefuroxime	3000 mg	9000 mg
Meropenem	2000 mg	6000 mg
Flucloxacillin	2000 mg	12,000 mg
Amoxicillin	2000 mg	12,000 mg
Amoxicillin/clavulanic acid	1000/200 mg + 1000 mg amoxicillin	4000/800 mg + 4000 mg amoxicillin
Piperacillin/tazobactam	8000/1000 mg	32,000/4000 mg

ISSN: 1471-2334