Table 2 Cytokine levels of study population stratified by the severity of SARS-CoV-2 infection
Cytokines | Mild/moderate (n = 160) | Severe/death (n = 42) |
|---|---|---|
BDNF | 73.02 (34.59, 187.07) | 110.56 (46.60, 301.73) |
EGF | 21.67 (6.54, 66.32) | 18.69 (5.53, 37.66) |
Eotaxin | 78.24 (36.08, 141.35) | 94.86 (55.38, 163.57) |
FGF-2 | OOR < (OOR <, 11.38) | OOR < (OOR <, 6.80) |
GM-CSF | 43.85 (7.08, 220.38) | 21.66 (OOR <, 67.10) |
GRO-α | 7.50 (OOR <, 27.42) | 7.63 (OOR <, 21.15) |
HGF | 272.18 (120.89, 698.81) | 609.71 (243.60, 1092.81) |
IFN-α | 1.17 (OOR <, 6.05) | 0.85 (OOR <, 3.32) |
IFN-γ | 16.66 (4.67, 57.78) | 18.90 (8.86, 41.84) |
IL-1-α | 0.41 (OOR <, 2.13) | 0.36 (OOR <, 1.86) |
IL-1-β | 5.80 (OOR <, 25.64) | 3.65 (OOR <, 13.68) |
IL-1RA | 1078.73 (498.40, 2100.30) | 1704.74 (796.54, 3459.01) |
IL-2 | 14.39 (OOR <, 62.00) | 6.24 (OOR <, 16.11) |
IL-4 | OOR < (OOR <, 42.16) | OOR < (OOR <, OOR <) |
IL-5 | 1.35 (OOR <, 35.47) | OOR < (OOR <, 13.73) |
IL-6 | 25.28 (OOR <, 219.44) | 26.22 (OOR <, 80.60) |
IL-7 | 3.62 (1.36, 9.35) | 3.09 (1.54, 6.60) |
IL-8 | 4.79 (OOR <, 13.35) | 6.75 (2.47, 14.50) |
IL-9 | OOR < (OOR <, 17.40) | OOR < (OOR <, OOR <) |
IL-10 | 1.79 (OOR <, 7.34) | 2.39 (0.93, 4.96) |
IL-12p70 | 0.68 (OOR <, 2.91) | 0.41 (OOR <, 1.12) |
IL-13 | 8.73 (OOR <, 29.76) | 6.32 (2.42, 16.44) |
IL-15 | 20.53 (1.88, 116.78) | 9.33 (1.10, 31.35) |
IL-17A | 17.11 (1.27, 78.41) | 6.20 (OOR <, 27.34) |
IL-18 | 33.40 (16.47, 60.64) | 36.83 (24.05, 67.07) |
IL-21 | OOR < (OOR <, 94.50) | OOR < (OOR <, 17.04) |
IL-22 | OOR < (OOR <, 44.69) | OOR < (OOR <, 12.42) |
IL-23 | OOR < (OOR <, 88.47) | OOR < (OOR <, OOR <) |
IL-27 | 33.31 (OOR <, 285.85) | OOR < (OOR <, 65.76) |
IL-31 | OOR < (OOR <, 126.79) | OOR < (OOR <, OOR <) |
IP-10 | 124.08 (55.83, 596.16) | 660.36 (212.48, 1617.52) |
LIF | 10.06 (3.83, 46.29) | 7.56 (4.28, 19.98) |
MCP-1 | 97.56 (51.85, 188.78) | 183.26 (84.34, 293.89) |
MIP-1-α | 14.38 (3.89, 42.40) | 12.57 (8.81, 38.50) |
MIP-1-β | 78.72 (31.46, 132.79) | 92.78 (66.13, 144.45) |
NGF-β | 6.19 (OOR <, 25.01) | OOR < (OOR <, 6.19) |
PDGF-BB | 234.62 (95.45, 602.95) | 267.38 (110.06, 1239.12) |
PIGF-1 | 13.62 (OOR <, 41.78) | 19.27 (OOR <, 57.38) |
RANTES | 612.82 (339.06, OOR >) | 696.85 (398.89, OOR >) |
SCF | 15.10 (7.20, 31.94) | 15.15 (9.25, 31.35) |
SDF-1-α | 675.14 (331.74, 978.67) | 794.22 (526.88, 1263.75) |
TNF-α | 5.84 (0.86, 31.01) | 4.72 (0.81, 9.44) |
TNF-β | OOR < (OOR <, OOR <) | OOR < (OOR <, OOR <) |
VEGF-A | 184.47 (86.27, 490.23) | 325.19 (194.84, 790.06) |
VEGF-D | OOR < (OOR <, 40.67) | 7.62 (OOR <, 35.50) |