Table 1 Underlying disease in severe Streptococcus dysgalactiae subsp. equisimilis bacteremia from August 2015 to July 2018, Pirkanmaa HD^a. Unadjusted and multivariable-adjusted logistic regression analysis was performed. All variables listed in the table, were included in multivariable-adjusted model. Results were shown using odds ratios (OR) with 95% confidence intervals (CI)

Gender

 Male

130

(60)

13

(59)

1.0

1.0

 Female

87

(40)

9

(41)

1.0

(0.4–2.5)

1.3

(0.4–4.1)

Age, years

 18–49

19

(8.8)

2

(9.1)

1.0

1.0

 50–64

31

(14)

2

(9.1)

0.6

(0.1–4.6)

0.3

(0.03–3.8)

 65–79

83

(38)

10

(45)

1.2

(0.2–5.8)

0.5

(0.1–4.1)

 ≥ 80

84

(39)

8

(36)

0.9

(0.2–4.6)

0.3

(0.03–3.5)

Obesity^c

98

(45)

8

(36)

0.7

(0.3-2.0)

1.1

(0.3–3.6)

Alcohol abuse

22

(10)

6

(27)

4.2

(1.4–12)

5.5

(1.1–28)

Malignancy

62

(29)

10

(45)

2.3

(0.9–5.6)

4.2

(1.3–13)

Cardiovascular diseases

97

(45)

14

(64)

2.4

(0.9–5.9)

1.4

(0.2–12)

 Coronary artery disease

53

(24)

9

(41)

2.4

(1.0-5.9)

1.7

(0.4–7.4)

 Chronic heart failure

74

(34)

11

(50)

2.1

(0.9–5.1)

2.2

(0.3–15)

Diabetes

81

(37)

10

(45)

1.5

(0.6–3.5)

1.5

(0.5–4.7)

Rheumatic disease

14

(6.5)

2

(9.1)

1.5

(0.3–7.3)

2.5

(0.3–22)

Chronic lung disease

37

(17)

6

(27)

2.0

(0.7–5.5)

1.6

(0.1-4)

 Asthma

20

(9.2)

2

(9.1)

1.0

(0.2–4.6)

0.5

(0.02-13)

 COPD

14

(6.5)

4

(18)

4.1

(1.2–14)

2.5

(0.1–57)

Chronic kidney disease

30

(14)

1

(4.5)

0.3

(0.04–2.1)

0.2

(0.02–1.6)

Chronic liver disease

10

(4.6)

2

(9.1)

2.3

(0.5–12)

0.7

(0.1–8.5)

Neurological disease

44

(20)

4

(18)

0.9

(0.3–2.7)

1.2

(0.3-5.0)

Immunosuppressive treatment^d

28

(13)

2

(9.1)

0.7

(0.1–2.9)

0.4

(0.1–3.1)