Designing a multi-epitope universal vaccine for concurrent infections of SARS-CoV-2 and influenza viruses using an immunoinformatics approach

Table 2 Evaluation of helper T-Lymphocyte epitopes derived from the nucleocapsid

Sequences	Immunogenicity	Antigenicity	Toxicity	Position	MHC-I alleles bind (IC₅₀< 200)
QIGYYRRATRRIRGG	Yes	Yes	No	83–97	HLA-DRB1*11:01;
NGGDAALALLLLDRL	Yes	Yes	No	213–227	HLA-DRB4*01:01;
DAALALLLLDRLNQL	Yes	Yes	No	216–230	HLA-DRB401:01, HLA-DRB103:01, HLA-DRB1*11:01,
GTWLTYTGAIKLDDK	Yes	Yes	No	328–342	HLA-DRB1*07:01,
TWLTYTGAIKLDDKD	Yes	Yes	No	329–343	HLA-DRB1*07:01

ISSN: 1471-2334